{"id":1655,"date":"2018-12-27T14:14:32","date_gmt":"2018-12-27T14:14:32","guid":{"rendered":"http:\/\/annsvg.com\/?p=1655"},"modified":"2018-12-27T14:14:39","modified_gmt":"2018-12-27T14:14:39","slug":"scientists-discover-groundbreaking-treatment-that-could-save-millions-from-cancer","status":"publish","type":"post","link":"https:\/\/annsvg.com\/index.php\/2018\/12\/27\/scientists-discover-groundbreaking-treatment-that-could-save-millions-from-cancer\/","title":{"rendered":"Scientists discover groundbreaking treatment that could save millions from Cancer"},"content":{"rendered":"\n

DAILYMAIL – A groundbreaking treatment for cancer which uses immune cells from strangers could save millions of lives in the future, scientists believe.<\/p>\n\n\n\n

The \ntreatment, still in its early days, will strengthen the immune systems \nof patients while avoiding toxic side effects such as those caused by \nchemotherapy.<\/p>\n\n\n\n

The team at the Francis \nCrick Institute in London now want to set-up the first immune banks \nwhich will store the ‘Natural Killer’ cells. <\/p>\n\n\n\n

This\n would allow oncologists to order a batch of immune cells to be \ndelivered to clinics in a matter of hours to then be infused into \npatients.<\/p>\n\n\n\n

Once in the body the cells \nwould join forces with the patient’s own immune system to fight off \ntumours using a natural ‘DIY’ approach.<\/p>\n\n\n\n

\"A<\/figure>\n\n\n\n

A groundbreaking treatment for \ncancer which transplants disease-fighting immune cells, which attack \ncancer cells, into the body of a patient from a stranger could save \nmillions of lives<\/p>\n\n\n\n

Professor Adrian Hayday, group leader of the Immunosurveillance Lab at The Crick, told The Telegraph<\/a>: ‘We’re not quite there yet.<\/p>\n\n\n\n

‘But that’s what we’re trying now. There is every capability of getting cell banks like this established.’<\/p>\n\n\n\n

Professor\n Hayday added that ‘even a few years ago’ there was little belief cancer\n could be tackled in any other way than attacking the disease itself.<\/p>\n\n\n\n

But now there is a growing field of \nresearch and experimental treatments focusing on training patients’ \nbodies to fight off cancers by themselves.<\/p>\n\n\n\n

Experts\n say this could become more effective than traditional treatments \nbecause bodies can adapt faster than medicine companies. <\/p>\n\n\n\n

Professor\n Hayday described the concept as ‘radical’ but added ‘that is what’s \nhappening’ now, with the cells not doing anything other than ramping up \nthe immune system.<\/p>\n\n\n\n

Cancer patients will\n begin to receive pioneering infusions of the so-called natural killer \ncells as early as next year, according to the researchers.<\/p>\n\n\n\n

Professor\n Charlie Swanton, of Crick’s Cancer Evolution and Genome Instability \nLaboratory said: ‘The future is incredibly bright.’<\/p>\n\n\n\n

\"The<\/figure>\n\n\n\n

The treatment was developed by scientists, led by Professor Adrian Hayday, at the Francis Crick Institute in London<\/p>\n\n\n\n

He\n added: ‘Using the body’s own immune cells to target the tumour is \nelegant because tumours evolve so quickly there is no way a \npharmaceutical company can keep up with it.<\/p>\n\n\n\n

‘But the immune system has been evolving for over four billion years to do just that.’ <\/p>\n\n\n\n

Until now, the idea of injecting someone’s immune cells into another person was dogged by fears the body would reject them.<\/p>\n\n\n\n

But this year, in a medical breakthrough, scientists discovered they survive well in the body and are unlike other cells.<\/p>\n\n\n\n

The\n Crick team are now seeing impressive results, particularly because the \ncells aren’t being rejected by the body, as is the case with some forms \nof immunotherapy.<\/p>\n\n\n\n

Immunotherapy drugs \nhelp the immune system work harder to find and kill cancer cells. But \nthere can be side effects because they attack healthy cells, too.<\/p>\n\n\n\n

The\n treatment is said to be the ultimate ‘do-it-yourself approach’ because \nit uses the patient’s own immune system and relies on no drugs. <\/p>\n\n\n\n

In England and Wales, survival rates for ten or more years after cancer are 50 per cent, according to Cancer Research UK.<\/p>\n\n\n\n

The\n team at The Crick want to make that figure rise to 75 per cent in the \nnext 15 years, and they claim advances in technology will make that \npossible.<\/p>\n\n\n\n

In the US, the five-year survival rate for all cancers combined is improving, and was 69 per cent between 2007 to 2013, according to the American Cancer Society.<\/p>\n\n\n\n

<\/p>\n\n\n\n

HOW DOES IMMUNOTHERAPY WORK? <\/h3>\n\n\n\n

 Immunotherapy uses our immune system to fight cancer. It works by helping the immune system recognise and attack cancer cells. <\/p>\n\n\n\n

Our\n immune system works to protect the body against infection, illness and \ndisease. It can also protect us from the development of cancer.<\/p>\n\n\n\n

The\n immune system includes the lymph glands, spleen and white blood cells. \nNormally, it can spot and destroy faulty cells in the body, stopping \ncancer developing. But a cancer might develop when:<\/p>\n\n\n\n

  • The immune system recognises cancer cells but it is not strong enough to kill the cancer cells<\/li>
  • The cancer cells produce signals that stop the immune system from attacking it <\/li>
  • The cancer cells hide or escape from the immune system   <\/li><\/ul>\n\n\n\n

    Immunotherapy\n is not yet as widely used as surgery, chemotherapy, and radiation \ntherapy. Chemotherapy uses medication to kill cancer cells and \nradiotherapy means the use of radiation, usually X-rays, to treat \nillness.<\/p>\n\n\n\n

    Immunotherapy uses the natural\n power of your immune system to fight illnesses, and has been approved \nto treat people with many types of cancer.<\/p>\n\n\n\n

    There are different types of immunotherapy, some of which are also called targeted therapies or biological therapies.<\/p>\n\n\n\n

     Monoclonal antibodies (MABs)   <\/p>\n\n\n\n

    Monoclonal\n antibodies are laboratory-produced molecules engineered to serve as \nsubstitute antibodies that can restore, enhance or mimic the immune \nsystem’s attack on cancer cells. <\/p>\n\n\n\n

    They \nare designed to bind to antigens that are generally more numerous on the\n surface of cancer cells than healthy cells. This process is called \nantibody dependent cell mediated cytotoxicity (ADCC).<\/p>\n\n\n\n

    Vaccines to treat cancer   <\/p>\n\n\n\n

    Normally,\n vaccines help to protect us from disease, and researchers are looking \nat whether vaccines can be used as a treatment to help the immune system\n to recognise and attack cancer cells.  <\/p>\n\n\n\n

    When\n you have the vaccine, it stimulates the immune system into action. The \nimmune system makes antibodies that can recognise and attack the \nharmless versions of the disease. <\/p>\n\n\n\n

    Once\n the body has made these antibodies it can recognise the disease if you \ncome into contact with it again. So you’re protected from it.<\/p>\n\n\n\n

    Cytokines <\/p>\n\n\n\n

    Cytokines are a group of proteins in the body that play an important part in boosting the immune system.<\/p>\n\n\n\n

    Interferon\n and interleukin are types of cytokines found in the body. Scientists \nhave developed man made versions of these to treat some types of cancer.<\/p>\n\n\n\n

     Adoptive cell transfer<\/p>\n\n\n\n

    Adoptive\n cell transfer changes the genes in a person’s white blood cells (T \ncells) to help them recognise and kill cancer cells. Changing the T cell\n in this way is called genetically engineering the T cell.<\/p>\n\n\n\n

    This\n treatment is only available as part of a clinical trial in the UK. An \nexample of a type of adoptive cell transfer is CAR T-cell therapy.<\/p>\n\n\n\n

     Source: Cancer Research UK<\/p>\n","protected":false},"excerpt":{"rendered":"

    DAILYMAIL – A groundbreaking treatment for cancer which uses immune cells from strangers could save millions of lives in the future, scientists believe. The treatment, still in its early days, will strengthen the immune systems of patients while avoiding toxic side effects such as those caused by chemotherapy. 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